CD80, also known as BB1/B7-1, is a 60kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on activated B cells, T cells, monocytes and dendritic cells. It is a ligand of the two T cell costimulatory molecules, CD28 and CD152 (CTLA-4). The interaction of CD80 (or CD86) with CD28 provides a costimulatory signal for T cells activated through the CD3/TCR complex.
Transfectant Cell Line: CHO
Functional Application: CD80-muIg fusion protein blocks binding of anti-human CD80 to human tumor cells.
Human CD80-muIg/Biotin Fusion Protein*
Molecular Structure: A soluble dimeric fusion protein consisting of the extracellular (173aa) domain of human CD80 fused to murine IgG2a Fc + hinge (232 aa). Predicted monomeric molecular weight: 51.3kD.
Applications:Suitable for use in ELISA, Flow cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer
仕様
Size：25ug
Source Antigen：CHO cells
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3.
