Programmed cell death 4 (PDCD4) encodes a tumor suppressor protein whose expression is lost in progressed carcinomas of lung, breast, colon, and prostate. The expression of PDCD4 gene is strongly induced during apoptosis in a number of cell types. It is modulated by cytokines in natural killer and T cells.
Location:19 amino acids near the carboxy terminus of human PDCD4
Applications:Peptide is used for blocking the activity of PDCD4 antibody (P3120-68). It usually blocks the antibody activity completely in Western Blot by incubating the peptide with equal volume of antibody for 30 min at 37˚C. Buffer is PBS containing 0.02% sodium azide. Other applications not tested.
Storage and Stability:May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:50ug
Source Antigen:Human synthetic peptide
Grade:Purified
Purity:Purified
Form:Supplied as a liquid in PBS, pH 7.2, 0.1% BSA and 0.02% sodium azide.