NcoR2 (nuclear receptor co-repressor) is a transcriptional corepressor that plays an essential role in the regulation of development and metabolism. The interaction of HDAC3 with the deacetylase activation domain (DAD) of NCOR2/SMRT is required for activation of the otherwise inert deacetylase. Recombinant human NCoR2 contains aa395-489 with an N-terminal GST tag (GenBank Accession No. NM_006312).
Applications:Useful for the study of enzyme kinetics, screening inhibitors and selectivity profiling.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
仕様
Size：50ug
Source Antigen：Recombinant, Expressed in E. coli
Grade：Purified
Purity：> 60% by SDS-PAGE
Form：Supplied as a liquid in 50mM Tris HCl, pH 8.0, 138mM sodium chloride, 0.1% Tween 20, 10% glycerol.
