85-1452-75　［取扱停止］S100 Calcium Binding Protein A11, Recombinant, Human (S100A11) 10ug　S0051-88

特徴

• S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.
• Description:The S100 family of proteins contain two EF-hand calcium-binding motifs and are thought to be involved in the regulation of a number of cellular processes including cell cycle progression and differentiation. This protein may function in motility, invasion and tubulin polymerisation. Recombinant Human S100A11 also called S100C is expressed in E. coli having a molecular weight of 17kD fused to an amino terminal hexahistidine tag.
• Applications:Suitable for use in Western Blot, ELISA, Immunoprecipitation and other Immunological experiments. Other applications not tested.
• Recommended Dilution:Western Blot: 2 bands at 17 and 34kD, respectively representing monomeric and dimeric form
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.