85-1448-10　［取扱停止］Atosiban, Human (ADH, Anti-Diuretic Hormone) 50mg　A4000-44

特徴

• Atosiban also called ADH (Anti-Diuretic Hormone) has a molecular formula of C43H67N11O12S2, Mpr-Tyr(OEt)-Ile-Thr-Asn-Cys-Pro-Orn-Gly-NH2 having a Mw of 994.2 is the first oxytocin antagonist to be specifically developed for the treatment of preterm labour. Atosiban has a specific mode of action, inhibiting oxytocin-induced uterine contractions lry blocking oxytocin receptors in the uterus. Extensive clinical investigations have shown Atosiban to be at least as effective as current tocolytic agents. In addition, due to its novel and specific mode of action, Atosiban has a markedly improved maternal side effects profile compared with conventional therapies.
• Solubility:It is recommended to reconstitute the lyophilized Atosiban in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
• Stability:Storage and Stability:Store powder dessicated at -20ºC. Liquid can be stored at 4ºC for 2-7 days, long term at -20ºC. For long term it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to prevent repeated freeze-thaw cycles
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