85-1447-69　［取扱停止］Actin-like Protein 6A, Recombinant, Human (ACTL6A, 53kD BRG1-associated Factor A, Actin-related Protein Baf53a) 10ug　A0760-95

特徴

• The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kD subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix.
• Description:Recombinant Human ACTL6A produced in E.Coli is a non-glycosylated, polypeptide chain containing 430 (1-429) amino acids and having a total molecular mass of 49.3kD. Recombinant ACTL6A contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.
• Applications:
• ELISA • Inhibition Assays • Western Blotting
• Stability:Recombinant ACTL6A although stable at 140C for 1 week, should be stored desiccated below -180C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.