BioAssay™ pre-developed human tissue arrays can be used to survey hundreds or even thousands of clinical specimens in a single experiment using common probes, such as DNA, RNA, peptide, protein and antibodies. Tissue arrays permit for a rapid and large-scale molecular analysis of tissue specimens with various probes in parallel. This powerful technique can be employed for verification and validation of gene discoveries and identification of potential diagnostic and therapeutic targets. It provides an effective assessment of the clinical significance of the molecular targets in cancer and other diseases at cellular and tissue levels. It is in-situ and in-vivo assay providing great clinical relevancy. BioAssay™ tissue chip lines bridge the gap between genomics and drug discovery, and effectively decrease time and cost of the drug discovery processes.
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Each single tissue core on every array slide is individually examined by pathologists certified according to WHO published standardizations of diagnosis, classification and pathological grade. Pathological re-confirmation report is generated and digital image captured. Before the array products are delivered to clients, standard immunohistochemistry tests and in situ hybridization tests are also performed to ensure the accuracy and specificity of tissue array products.
Neutral formalin-fixation and paraffin-embedding procedures have been applied to all specimens obtained from clinics. Consequently, no living organism would exist on any paraffin-embedded arrays.
Each specimen collected from any clinic was consented to by both hospital and individual. Discrete legal consent form was obtained and the rights to hold research uses for any purpose or further commercialized uses were waived.
