Adipocyte fatty acid binding protein FABP5 is a 15kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds ( bile acids or retinoids). in an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (FABP5) are closely related and both are expressed in adipocytes. Absence of FABP5/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systemic insulin sensitivity.
Applications:Suitable for use in Western Blot and ELISA. Other applications have not been tested
Optimal dilutions to be determined by researcher
Storage and Stability:Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. The lyophilized protein remains stable at least 12 months when stored at -20°C.
仕様
Size：100ug
Source Antigen：Human recombinant protein expressed in E. coli.
Grade：Affinity Purified
Purity：>90% (SDS-PAGE). Two-step procedure using size exclusion chromatography before and after refolding.
Form：Supplied as a lyophilized powder from PBS. Reconstitute with 0.2ml of sterile ddH20 and let the lyophilized pellet dissolve completely.
Specificity：The amino acid sequence of the recombinant human EFABP is 100% homologous to the amino acid sequence of the human EFABP.
