85-1440-01　［取扱停止］Hepatitis A Virus VP4-VP2, aa55-164, Recombinant (HAV) 100ug　H1900-49A

特徴

• HAV, the prototype of the genus Hepatovirus, belongs to the family Picornaviridae. Its 7.5-kb single-stranded RNA genome bears different distinct regions: the 5' and 3' noncoding regions (NCR), the P1 region, which encodes the structural proteins VP1, VP2, VP3, and a putative VP4, and the P2 and P3 regions encoding nonstructural proteins associated with replication. Hepatitis A virus (HAV) encodes a single polyprotein which is posttranslationally processed into the functional structural and nonstructural proteins. Only one protease, viral protease 3C, has been implicated in the nine protein scissions.
• Recombinant corresponding to aa55-164 of HAV structural proteins VP2-VP4 immunodominant regionsexpressed in E. coli.
• Immunoreactive with sera of HAV-infected individuals.
• Applications:Suitable for use in ELISA and Western Blot. Excellent antigen for detection of HAV with minimal specificity problems. Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.