Human casein kinase 1 delta is also known as protein kinase CK1 delta. The casein kinase 1 family of protein kinases is common to all eukaryotic cells, although tissue distribution and subcellular localization may vary between isoforms. Casein kinase 1 delta has been implicated in the regulation of p53. Upregulation of casein kinase 1 delta expression has been reported in Alzheimer's disease hippocampus and its association with tau-containing bodies suggests that it may play a role in the abnormal phosphorylation of tau.
Source:Recombinant corresponding to aa1-415, full length of human Casein Kinase 1 delta (NT: T7 tag) expressed in E. coli (NP_001884.1).
Applications:Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard. Other applications not tested.
Quality Control:SDS-PAGE
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Important Note: This recombinant enzyme has NOT been tested with regard to biological activity.
仕様
Size:50ug
Source Antigen:Recombinant, E. coli
Grade:Highly Purified
Purity:~95%
Form:Supplied as a liquid in Tris, pH 8.0, 0.1% Triton X-100, 0.02% sodium azide, 10mM DTT.