The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
Control Peptide for Opioid Receptor, delta, O7030-05Peptide Sequence (linear):Synthetic peptide:TACTPSDGPGGGAAA, corresponding to amino acids 358-372 of Rat Delta Opioid Receptor
Purity: >99% HPLC
100%Form:Supplied as a lyophilized powderMolecular Weight:1233DStorage and Stability:Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：1mg
Source Antigen：Synthetic peptide
Grade：Purified
Purity：Purified (HPLC)
Form：Lyophilized. Reconstitute initially in a small volume of 25% acetonitrile in water or 25% ethanol in water to make a concentrated stock solution and dilute aqueous buffer.
