The neuronal version of human IL-16 (NIL-16), identical to the splenocyte-derived pro IL-16 in its C-terminal 624 amino acids, has an N-terminal portion containing multiple PDZ domains. mRNA for NIL-16 has been localized to cerebellar and hippocampal neurons. It is thought that NIL-16 plays a dual role by serving as a clustering protein for ion channels as well as signaling molecule after proteolysis by caspase-3.
Control peptide DEKYPDPFETSLC (linear) for corresponding antibody I8438-20.
Application(s): Suitable for use in Immunization and as a control peptide.
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.