Control peptide for M9515-01 which recognizes Musashi RNA Binding Protein in human and rodent.
Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia and Parkinson's. The presence of Msi-1 in a significant percentage of neurons containing cytoplasmic inclusions in 2 other neurodegenerative diseases Alzheimer's disease and Pick disease suggests that it may play a role in the pathogenesis of these neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play a vital role in the development of several types of carcinoma such as human hepatoma and may be a useful molecular marker for tumor detection.
Applications:Suitable for use in ELISA, Western Blotting. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
仕様
Size：1mg
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in MES pH5. Conjugated to BSA.
