Tissue Plasminogen Activator (tPA) is tissue specific for activation of plasminogen. The kringle-2 domain of tPA reacts with lysine residues on the fibrin forming an activated complex. tPA is a single chain molecule that is cleaved to the active two-chain form by the action of the plamin pathway. tPA primarily exists coupled to PAI-1 in circulation. tPA is completely complexable with human PAI-1
Specific Activity:As Reported
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Source Antigen：Recombinant, Chinese hamster ovary (CHO) cells
Grade：Highly Purified
Purity：≥95% (SDS-PAGE)
Form：Supplied as a liquid in 0.4M HEPES, 0.1M sodium chloride, pH 7.4.
