85-1408-95　Plasminogen Activator Inhibitor Type 1, active wild type, Human Recombinant (PAI-1) 500ug　P4256-29B

特徴

• Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma that is implicated in the processes of angiogenesis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation (1). The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer (2,3,4). PAI-1 is activated by the glycoprotein vitronectin. Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration (5). This binding has proven to be an important inhibitor of the activated form of protein C (APC) (6).
• Activity:≥ 98% by SDS PAGE
• Appearance:Colorless frozen solution
• Solubility:> 2mg/ml and < 5mg/ml
• Storage and Stability:For long-term storage, aliquot and store at -70°C. Aliquots are stable for 6 months after receipt at -70°C. Further dilutions can be made in assay buffer.

仕様

• Size：500ug
• Source Antigen：Recombinant, E. coli
• Grade：Highly Purified
• Purity：≥ 98% pure by SDS PAGE.
• Form：Supplied as a liquid in PBS, 1mM EDTA, pH 6.6.
• Molecular Weight Non Ab：43
• EU Commodity Code：30021019
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