A 16aa peptide sequence (designated TIT11-P; control peptide), near the C-terminal, cytoplasmic domain of rat TIT. The 16-aa rat peptide sequence is unique to TIT and no significant sequence is seen with glucose transporter or other Na+-dependent transporters.
Iodide (I-) is an essential constituent of thyroid hormones. Thyroid epithelial cells for the biosynthesis of thyroid hormones actively transport it. At the cellular level, Iodide transport is mediated by intrinsic membrane Na+/I+ symporter (NIS). Rat TIT (618 aa; ~66kD) is predicted to contain 12 transmembrane domains. Both N and C-termini are predicted to be cytoplasmic.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：100ug
Source Antigen：Rat synthetic peptide
Grade：Highly Purified
Purity：Highly purified
Form：Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
