85-1382-33　hSOS, aa1149-1158 1mg　H7650

特徴

• SH3 binding sequence of guanine nucleotide exchange factor hSOS; blocks binding of hSOS1 to human Grb2, preventing Ras activation via receptor protein tyrosine kinases. Grb2 acts as an adaptor protein in the transduction of signals from receptor tyrosine kinases to Ras. It binds to phosphotyrosine on the cytoplasmic tail of cell-surface receptors via its central SH2 domain, and to its immediate downstream target, Sos, via two SH3 domains.
• Sequence (linear): Val-Pro-Pro-Pro-Val-Pro-Pro-Arg-Arg-Arg-OH
• Amino Acid Analysis: Confirms expected sequencePeptide Content: 84.9 ± 4%
• Solubility: H2O
• Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：1mg
• Grade：Highly Purified
• Purity：95+% HPLC, Mass Spec
• Form：Supplied as a white to off-white lyophilized powder.
• Molecular Weight Non Ab：1170
• EU Commodity Code：38220090
• この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]