Ang II plays an important role in regulating natriuretic peptide gene expression during cardiac overload. ANP and BNP gene expression in the rat heart is modulated by the adrenal factors during Ang II-stimulated hemodynamic stress and the AT1 receptor antagonism in NO-deficient hypertension. Moreover, ventricular BNP gene expression in Ang II-induced hypertension in vivo is controlled by posttranscriptional mechanisms and GATA elements.
AA Sequence: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt
The sequence given for angiotensin II corresponds to the sequences of human, horse, sheep, pig and rat angiotensins.
Identification:m=1046.3u (average mass)
Water (KF):3.0%
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only. Reconstitute with sterile distilled water and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：25mg
Grade：Molecular Biology Grade
Purity：≥ 98% (TEAP; HPLC)
Form：Supplied as a lyophilized powder. Reconstitute to 10mg/ml with sterile ddH2O.
