85-1365-01　Penicillin G, Sodium Salt USP 1Kg　CAS No:69-57-8　P3200

特徴

• Penicillin G is a broad based antibiotic used in mammalian cell culture. Penicillin G blocks the formation of bacterial cell walls, rendering bacteria unable to multiply and spread. The spectrum of activity of Penicillin G includes many aerobic and anaerobic gram-positive organisms. Aerobes susceptible to Penicillin G include most beta-hemolytic streptococci, beta-lactamase-negative staphylococci, Actinomyces species, some Bacillus anthracis, Corynebacterium species, and Erysipelothrix rhusiopathiae. Most species of anaerobes, including Clostridium species, but excluding beta-lactamase-producing Bacteroides species, are also susceptible to Penicillin G. Penicillin G is easily inactivated by beta-lactamases and has little efficacy against organisms that can produce these enzymes. In addition, Penicillin G is ineffective against those bacteria that are resistant by other mechanisms, such as having a relatively impermeable cell wall. Therefore, Penicillin G has little activity against many staphylococci and most gram-negative bacteria.
• Synonyms:(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenylacetyl)amino]- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium; 3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt; (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Monosodium Salt; American Penicillin; Benzylpenicillin Sodium; Benzylpenicillin Sodium Salt; Benzylpenicillinic Acid Sodium Salt; Crystapen; Ethacillin; Monocillin; Monosodium Benzylpenicillin; Mycofarm; Nalpen G; Nobak; Novocillin; Pen-A-Brasive; Penicillin G Sodium; Penilaryn; Sodium 6-(Phenylacetamido)penicillanate; Sodium Benzylpenicillin; Sodium Benzylpenicillin G; Sodium Benzylpenicillinate
• Molecular Formula:C16H17N2O4NaS
• Molecular Weight:356.37
• Purity:96-102.0%
• Appearance:White to off white crystalline powder
• Solubility:Soluble in water, slightly soluble in ethanol, insoluble in methylene chloride
• Identification:Conforms to USP
• Melting Point:>209°C (dec.) (lit)
• Specific Rotation:+285 to +310°
• pH:5.5-7.5
• Loss on Drying:≤1%
• Related Substances:≤1%
• 2-Ethylhexanoic Acid:≤0.5%
• Endotoxin:≤0.5U/mg
• Storage and Stability:Powder may be stored at 4°C. Stable for 12 months after receipt at 4°C.