FABP is a plasma marker of acute myocardial infarction (AMI). The plasma kinetics of FABP (15kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. The concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), making FABP cardiac-specific cf. myoglobin. This makes FABP a useful biochemical marker for the early assessment or exclusion of AMI. FABP also appears a useful plasma marker for the estimation of myocardial infarct size.
Applications:Suitable for use as standard in ELISA and other immunoassays, immunogen for antisera production, and tracer for Iodination. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Source Antigen:Human heart tissue
Grade:Highly Purified
Purity:Highly purified (≥98%). No contaminants detected by SDS-PAGE.
Form:Supplied as a lyophilized powder in 10mM Tris-HCl, pH 8.0. No preservatives added. Reconstitute with sterile distilled water.