特徴
- 背景:The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication.
- PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.
- Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
仕様
- サイズ:50ug
- 種由来:SARS-CoV-2
- 発現宿主:E.coli
- 純度:>90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:QHD43415.1
- アミノ酸配列:Glu1024-Gln1198
- 遺伝子構造:Recombinant SARS-CoV-2 NSP3 is produced by E.coli expression system and the target gene encoding Glu1024-Gln1198 is expressed with N-His Tag
- 別名(遺伝子名):nsp3,PL-PRO,Papain-like proteinase,X domain(Macro domain)
- 分子量:22.03kDa
- 組成:Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9376-19
Recombinant SARS-CoV-2 NSP3 protein 100ug
|
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84-9376-18
Recombinant SARS-CoV-2 NSP3 protein 50ug
|
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