84-9375-03 ［取扱停止］Recombinant Rat TNF-alphasf protein（His tag） 20ug PKSR500005
[Elabscience]
特徴
- 背景：Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR.
- It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines.
- It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake.
- Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance.Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
仕様
- サイズ：20ug
- 種由来：Rat
- 発現宿主：E.coli
- 純度：＞85 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：Please contact us for more information.
- アクセッションNo.：P16599
- アミノ酸配列：Gly57-Leu235
- 遺伝子構造：A DNA sequence encoding theRat TNF-alphasf protein （P16599） （Gly57-Leu235） was expressed with a N-His.
- 別名（遺伝子名）：Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a;N-terminal fragment;NTF;ICD1;ICD2
- 分子量：19.7 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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84-9375-04
Recombinant Rat TNF-alphasf protein（His tag） 100ug
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84-9354-83
Recombinant Rat TNF-alphasf protein（His tag） 100ug
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84-9375-03
Recombinant Rat TNF-alphasf protein（His tag） 20ug
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84-9354-82
Recombinant Rat TNF-alphasf protein（His tag） 20ug
|
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