背景：The cluster of differentiation （CD） system is commonly used as cell markers in immunophynotyping.
Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell.
There are more than 320 CD unique clusters and subclusters have been identified.
Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell.
Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion.
CD124, also known as interleukin 4 receptor （IL4R）, is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4.
The membrane-bound form of CD124 can be hydrolyzed to soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.
仕様
サイズ：50ug
種由来：Rat
発現宿主：HEK293 Cells
純度：＞90 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：Q63257-1
アミノ酸配列：Met1-Arg232
遺伝子構造：A DNA sequence encoding the rat IL4R （Q63257-1） （Met1-Arg232） was expressed with the Fc region of human IgG1 at the C-terminus.
別名（遺伝子名）：IL4R;Il4ra
分子量：50.9 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
