背景：The cluster of differentiation （CD） system is commonly used as cell markers in immunophynotyping.
Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell.
There are more than 320 CD unique clusters and subclusters have been identified.
Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell.
Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion.
Cluster of differentiation 10 （CD10）, also known as Neprilysin and neutral endopeptidase, is a member of the CD system.
CD10 is a zinc-dependent metalloprotease enzyme that had function to degrade a number of small secreted peptides such as the amyloid beta peptide.
It exist as a membrane-bound protein and have high concentration in kidney and lung tissues.
Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process.
CD10 is also associated with other biochemical processes.
仕様
サイズ：50ug
種由来：Rat
発現宿主：HEK293 Cells
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：P07861
アミノ酸配列：Tyr52-Trp750
遺伝子構造：A DNA sequence encoding the rat MME （P07861） （Tyr52-Trp750） was expressed with a polyhistidine tag at the N-terminus.
別名（遺伝子名）：MME
分子量：82.5 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
