84-9372-87 Recombinant Mouse IL-15 protein（N-His）（active） 100ug PKSM041466
[Elabscience]
特徴
- 背景：Human Interleukin 15 （IL-15） is a cytokine that regulates T cell and natural killer cell activation and proliferation.
- IL-15 binds to the alpha subunit of the IL15 receptor （IL-15RA） with high affinity.
- IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor.
- IL-15 is structurally and functionally related to IL-2.
- Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other＆#39;s activity.
- The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2.
- Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system.
- IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs.
- Mature Human IL-15 shares 70％ amino acid sequence identity with Mouse and Rat IL-15.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：＞98 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜0.1 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P48346
- アミノ酸配列：MKILKPYMRNTSISCYLCFLLNSHFLTEAGIHVFILGCVSVGLPKTEANWIDVRYDLEKIESLIQSIHIDTTLYTDSDFHPSCKVTAMNCFLLELQVILHEYSNMTLNETVRNVLYLANSTLSSNKNVAESGCKECEELEEKTFTEFLQSFIRIVQMFINTS
- 別名（遺伝子名）：IL-15;Interleukin 15;IL15
- 分子量：19.42 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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84-9372-86
Recombinant Mouse IL-15 protein（N-His）（active） 20ug
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84-9372-87
Recombinant Mouse IL-15 protein（N-His）（active） 100ug
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