特徴
- 背景：Growth-regulated alpha protein （CXCL1,KC）, is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor.
- The N-terminal processed form KC（5-72） of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity.
- Mouse KC shows approximately 63％ identity to that of mouse MIP-2.
- KC is also approximately 60％ identical to the human GROs.
- It has been suggested that mouse KC and MIP-2 are the orthologs of the human GROs and rat CINCs.
- Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation.
- Hematoregulatory chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation.
仕様
- サイズ：20ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜0.1 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P12850
- アミノ酸配列：MIPATRSLLCAALLLLATSRLATGAPIANELRCQCLQTMAGIHLKNIQSLKVLPSGPHCTQTEVIATLKNGREACLDPEAPLVQKIVQKMLKGVPK
- 別名（遺伝子名）：Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha（1-73）; Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
- 分子量：11.08 kDa
- 組成：Lyophilized from a solution containing 50 mM Tris and 150 mM NaCl, pH 8.5.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9372-81
Recombinant Mouse CXCL1 protein（N-His）（active） 100ug
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84-9372-80
Recombinant Mouse CXCL1 protein（N-His）（active） 20ug
|
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