84-9372-46 Recombinant Mouse Interleukin-13/IL-13 Protein (Active) 20ug PKSM041322
[Elabscience]特徴
- 背景:Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells.
- IL-13 induces B cell proliferation and immunoglobin production.
- It contains a four helical bundle with two internal disulfide bonds.
- Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity.
- IL13 signals via receptor IL13R (type2, IL4R) and activates STAT-6.
- IL13 initially binds IL-13Rα1 with low affinity and triggers association of IL4Rα, generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals.
- IL13 also binds IL-13Rα2 with high affinity, which plays a role in a negative feedback system of IL13 signaling.
- IL13 is an important mediator of allergic inflammation and disease.
仕様
- サイズ:20ug
- 種由来:Mouse
- 発現宿主:E.coli
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:P20109
- アミノ酸配列:Pro22-Phe131
- 遺伝子構造:Recombinant Mouse Interleukin-13 is produced by our E.coli expression system and the target gene encoding Pro22-Phe131 is expressed.
- 別名(遺伝子名):Interleukin-13; IL-13; T-Cell Activation Protein P600; Il13; Il-13
- 分子量:12.2 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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84-9372-47
Recombinant Mouse Interleukin-13/IL-13 Protein (Active) 100ug
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84-9372-46
Recombinant Mouse Interleukin-13/IL-13 Protein (Active) 20ug
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