背景：Tumor necrosis factor alpha （TNF-alpha）, also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation.
Two receptors, TNF-R1 （TNF receptor type 1; CD120a; p55/60） and TNF-R2 （TNF receptor type 2; CD120b; p75/80）, bind to TNF-alpha.
TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 （IL-1）.
TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
TNF-alpha Protein ＆amp; Antibody
仕様
サイズ：20ug
種由来：Mouse
発現宿主：E.coli
純度：＞98 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：Please contact us for more information.
アクセッションNo.：NP_038721.1
アミノ酸配列：Leu 80-Leu 235
遺伝子構造：A DNA sequence encoding the soluble form of mouse TNF-α （NP_038721.1） （Leu 80-Leu 235） was expressed, with an initial Met at the C-terminus.
組成：Lyophilized from sterile 50mM Tris 0.2M NaCl, pH 7.2
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
