84-9372-34 Recombinant Mouse Interleukin-33/IL-33 Protein （Active） 100ug PKSM041090
[Elabscience]
特徴
- 背景：Mouse Interleukin 33 （IL-33） is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells.
- IL-33 is constitutively expressed in smooth muscle and airway epithelia.
- IL-33 was identified based on sequence and structural homology with IL-1 family cytokines.
- It is up-regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL-1 beta stimulation.
- IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1.
- BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines.
- In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：Q8BVZ5
- アミノ酸配列：Ser109-Ile266
- 遺伝子構造：Recombinant Mouse Interleukin-33 is produced by our E.coli expression system and the target gene encoding Ser109-Ile266 is expressed.
- 別名（遺伝子名）：Interleukin 33; IL-33; IL33; C9orf26; NKHEV; Interleukin-1 family member 11; DVS27; NF-HEV and IL- 1F11
- 分子量：17.6 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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84-9372-33
Recombinant Mouse Interleukin-33/IL-33 Protein （Active） 20ug
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84-9372-34
Recombinant Mouse Interleukin-33/IL-33 Protein （Active） 100ug
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