特徴
- 背景:Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family.
- CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells.
- It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it.
- CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response.
- It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases.
- it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.
仕様
- サイズ:100ug
- 種由来:Mouse
- 発現宿主:E.coli
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:P18340
- アミノ酸配列:Thr22-Thr126
- 遺伝子構造:Recombinant Mouse C-X-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Thr22-Thr126 is expressed.
- 別名(遺伝子名):C-X-C motif chemokine 9;Cxcl9;Gamma-interferon-induced monokine;Monokine induced by interferon-gamma;MIG;Small-inducible cytokine B9;Scyb9
- 分子量:12.3 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9372-15
Recombinant Mouse CXCL9 Protein 20ug
|
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84-9372-16
Recombinant Mouse CXCL9 Protein 100ug
|
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