背景:ENPEP, also known as aminopeptidase A, is a member of the peptidase M1 family.
Members of this family are involved in response to cadmium ion and proteolysis.
They located in 6 components and are expressed in 26 plant structures.
ENPEP is expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron.
It also can be detected in a variety of other tissues.
ENPEP probably plays a role in regulating growth and differentiation of early B-lineage cells.
It also may play a role in the catabolic pathway of the renin-angiotensin system.
ENPEP is a zinc-dependent membrane-bound aminopeptidase that catalyzes the cleavage of glutamatic and aspartatic amino acid residues from the N-terminus of polypeptides.
It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
仕様
サイズ:50ug
種由来:Mouse
発現宿主:Baculovirus-Insect Cells
純度:>91 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.:P16406
アミノ酸配列:Arg41-Pro945
遺伝子構造:A DNA sequence encoding the mature form of mouse ENPEP (P16406) (Arg41-Pro945) was expressed, with a polyhistidine tag at the N-terminus.
組成:Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.