84-9371-73 Recombinant Mouse CD38 Protein （His Tag）（Active） 500ug PKSM040814
[Elabscience]
特徴
- 背景：The cluster of differentiation （CD） system is commonly used as cell markers in immunophynotyping.
- Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell.
- There are more than 320 CD unique clusters and subclusters have been identified.
- Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell.
- Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion.
- Cluster of differentiation 38 （CD38）, also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells （white blood cells）, including CD4+, CD8+, B and natural killer cells.
- It shares several characteristics with ADP-ribosyl cyclase 2 CD157.
- CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose （cADPR） from NAD+ to ADP-ribose.
- It also functions in cell adhesion, signal transduction and calcium signaling.
- CD38 has been used as a prognostic marker in leukemia.
- It can also be used to identify plasma cells.
仕様
- サイズ：500ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：＞97 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：NP_031672.2
- アミノ酸配列：Leu 45-Thr 304
- 遺伝子構造：A DNA sequence encoding the extracellular domain of mouse CD38 （NP_031672.2） （Leu 45-Thr 304） was expressed, fused with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：cADPr hydrolase 1; CD38 antigen （p45）; CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC 3.2.2.5; NAD（+） nucleosidase; T10;;ADPRC 1-rs1;ADPRC1;Cd38;Cd38-rs1;I-19
- 分子量：31.3 kDa
- 組成：Lyophilized from sterile 20mM MES, 0.15M NaCl, pH 6.5
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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84-9371-73
Recombinant Mouse CD38 Protein （His Tag）（Active） 500ug
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84-9371-72
Recombinant Mouse CD38 Protein （His Tag）（Active） 50ug
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