背景：The carbonic anhydrases （or carbonate dehydratases） are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues.
The carbonic anhydrasekl （CA） family consists of at least 11 enzymatically active members and a few inactive homologous proteins.
Carbonic anhydrase IV （CAIV） is a membrane-associated enzyme anchored to plasma membrane surfaces by a phosphatidylinositol glycan linkage.
CAIV is a high-activity isozyme in CO2 hydration comparable to that of CAII.
Furthermore, CAIV is more active in HCO3- dehydration than is CAII.
However, the esterase activity of CAIV is decreased 150-fold compared to CAII.
仕様
サイズ：50ug
種由来：Mouse
発現宿主：HEK293 Cells
純度：＞98 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_031633.1
アミノ酸配列：Met 1-Ser 277
遺伝子構造：A DNA sequence encoding the mouse Car4 （NP_031633.1） without the C-terminal propeptide （Met 1-Ser 277） was expressed,with a C-terminal polyhistidine tag.
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
