背景:Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein which belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3.
It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247).
PRSS2 contains onepeptidase S1 domain.
It is secreted into theduodenum,hydrolysing peptides into their smaller building blocks, which is necessary for the uptake of protein in the food.
It is secreted by the pancreas in the form of inactivezymogen,trypsinogen and cleaved to its active form in the small intestine when the pancreas is stimulated bycholecystokinin through the common activation mechanism.
仕様
サイズ:50ug
種由来:Mouse
発現宿主:HEK293 Cells
純度:>92 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.:NP_033456.1
アミノ酸配列:Met 1-Asn 246
遺伝子構造:A DNA sequence encoding the mouse PRSS2 (NP_033456.1) precursor (Met 1-Asn 246) was expressed, with a C-terminal polyhistidine tag.
別名(遺伝子名):Prss2;Ta;Tesp4;Try2;TRY8;TRYP
分子量:26.2 kDa
組成:Lyophilized from sterile PBS, pH 7.5
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.