84-9371-52 Recombinant Mouse CD39/ENTPD1 Protein （His Tag）（Active） 50ug PKSM040702
[Elabscience]
特徴
- 背景：CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family.
- It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues.
- The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only.
- CD39 can hydrolyze both nucleoside triphosphates and diphosphates.
- It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic （P2） G protein coupled receptors （GPCRs）.
- CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism.
- There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis.
- In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Baculovirus-Insect Cells
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P55772
- アミノ酸配列：Thr 38-Ile 478
- 遺伝子構造：A DNA sequence encoding the mouse ENTPD1 （P55772） extracellular domain （Thr 38-Ile 478） was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
- 別名（遺伝子名）：Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39
- 分子量：51 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10％ gly
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
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84-9371-52
Recombinant Mouse CD39/ENTPD1 Protein （His Tag）（Active） 50ug
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84-9371-53
Recombinant Mouse CD39/ENTPD1 Protein （His Tag）（Active） 500ug
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