背景:The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues.
The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins.
Carbonic anhydrase II is one of fourteen forms of human α carbonic anhydrases.
Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.
Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule.
Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.
仕様
サイズ:1mg
種由来:Mouse
発現宿主:E.coli
純度:>96 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:Please contact us for more information.
アクセッションNo.:AAH55291.1
アミノ酸配列:Met 1-Lys 260
遺伝子構造:A DNA sequence encoding the mouse CA2 (AAH55291.1) (Met 1-Lys 260) was expressed, with a C-terminal polyhistidine tag.
別名(遺伝子名):AI131712;Ca2;CAII;Car-2;Ltw-5;Lvtw-5
分子量:30.4 kDa
組成:Lyophilized from sterile 50mM Tris, 150mM NaCl, pH 7.5
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.