背景：CLEC10A, also known as the macrophage galactose-type calcium-type lectins （MGLs; CD301） constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues.
MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells （DCs）.
There are 2 homologues： MGL1 and MGL2 （CD301a and CD301b） in mice.
MGL1/CD301a induces both the production and secretion of interleukin （IL）-10.
MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
仕様
サイズ：1mg
種由来：Mouse
発現宿主：HEK293 Cells
純度：＞97 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_001191181.1
アミノ酸配列：Gln 58-Ser 305
遺伝子構造：A DNA sequence encoding the extracellular domain of mouse CLEC10A （NP_001191181.1） （Gln 58-Ser 305） was fused with a polyhistidine tag at the N-terminus.
別名（遺伝子名）：CD301a;M-ASGP-BP-1;Mgl;Mgl1
分子量：30.7 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
