背景：Vinculin （VCL） is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions.
VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton.
The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment.
This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.
仕様
サイズ：50ug
種由来：Mouse
発現宿主：HEK293 Cells
純度：＞90 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：NP_033528.3
アミノ酸配列：Met1-Gln1066
遺伝子構造：A DNA sequence encoding the mouse VCL （NP_033528.3） （Met1-Gln1066） was expressed with a C-terminal polyhistidine tag.
別名（遺伝子名）：9430097D22;AA571387;AI462105;AW545629
分子量：118.2 kDa
組成：Lyophilized from sterile PBS, pH 7.4
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
