84-9370-48　［取扱停止］Recombinant Human CLDN1 protein（His tag） 100ug　PKSH500084

特徴

• 背景：Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia.
• While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules.
• Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability.
• CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin.
• Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.

仕様

• サイズ：100ug
• 種由来：Human
• 発現宿主：E.coli
• 純度：＞90 ％ as determined by reducing SDS-PAGE.
• エンドトキシン濃度：Please contact us for more information.
• アクセッションNo.：O95832
• アミノ酸配列：Gln29-Lys115
• 遺伝子構造：A DNA sequence encoding theHuman CLDN1 protein （O95832） （Gln29-Lys115） was expressed with a N-His.
• 別名（遺伝子名）：Senescence-associated epithelial membrane protein
• 分子量：9.6 kDa
• 組成：Lyophilized from sterile PBS, pH 7.4.
• 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
• メーカーマニュアルリンク：メーカーマニュアルはこちら
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]