特徴
- 背景：Cytokine with antiviral, antitumour and immunomodulatory activities.
- Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues.
- Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes （ISG）, which mediate the antiviral state.
- Has a restricted receptor distribution and therefore restricted targets： is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1.
- Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：Q8IU54
- アミノ酸配列：Met1-Thr200
- 遺伝子構造：A DNA sequence encoding the Human IL-29 Protein（Q8IU54）（1-200）was expressed with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：Interferon lambda-1,IFN-lambda-1,ytokine Zcyto21,Interleukin-29,IL29,IFNL1,ZCYTO21
- 分子量：22 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4., 5％ trehalose, 5％ mannitol, 0.01％ tween-80.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
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- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9357-10
Recombinant Human IL-29 Protein 100ug
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84-9369-45
Recombinant Human IL-29 Protein 100ug
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84-9357-09
Recombinant Human IL-29 Protein 20ug
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84-9369-44
Recombinant Human IL-29 Protein 20ug
|
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