特徴
- 背景:This gene is a classical cadherin from the cadherin superfamily.
- The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.
- Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer.
- Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis.
- The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization.
- Identified transcript variants arise from mutation at consensus splice sites.
仕様
- サイズ:20ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:P12830-1
- アミノ酸配列:Asp155-Phe375
- 遺伝子構造:A DNA sequence encoding the Human CDH1 (P12830-1) (Asp155-Phe375) was expressed with a polyhistidine tag at the N-terminus.
- 別名(遺伝子名):Arc 1,CADH1,Cadherin 1,cadherin 1 type 1 E-cadherin,Cadherin1,CAM 120/80,CD 324,CD324,CD324 antigen,cdh1,CDHE,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,epithelial calcium dependant adhesion protein,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin
- 分子量:23.9kDa
- 組成:Lyophilized from sterile PBS, pH 7.4.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
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- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
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84-9344-10
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84-9369-21
Recombinant Human CDH1 Protein (His Tag) 20ug
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84-9344-11
Recombinant Human CDH1 Protein (His Tag) 100ug
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