特徴
- 背景:Human NEDD8 shares 60% amino acid sequence identity to ubiquitin.
- The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases.
- The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation.
- NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:Q15843
- アミノ酸配列:Met1-Gly76
- 遺伝子構造:Recombinant Human Neural precursor cell expressed developmentally down-regulated protein 8 is produced by our E.coli expression system and the target gene encoding Met1-Gly76 is expressed.
- 別名(遺伝子名):Neural precursor cell expressed developmentally down-regulated protein 8; NEDD8; Neddylin; Ubiquitin-like protein Nedd8
- 分子量:8.6 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 250mM NaCl, pH 8.0.
- 保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
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- TEL:06-6447-8641
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- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9366-97
Recombinant Human NEDD8 10ug
|
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84-9366-98
Recombinant Human NEDD8 50ug
|
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