背景:The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors.
ILTs are expressed on many leukocyte subsets and regulators of immune responses .
ILTs share significant homology with killer cell Ig-like receptors (KIR).
Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains .
ILT2 is expressed on most monocytes,dendritic cells,and mature B cells.
ILT2 is also expressed on small percentages of T-cells and NK cells.
ILT2 can prevents cellular activation.
仕様
サイズ:10ug
種由来:Human
発現宿主:HEK293 Cells
純度:>95 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.:D9IDM8
アミノ酸配列:Gly24-His458
遺伝子構造:Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 is produced by our Mammalian expression system and the target gene encoding Gly24-His458 is expressed with a Fc tag at the C-terminus.
別名(遺伝子名):Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; CD85 Antigen-Like Family Member J; Immunoglobulin-Like Transcript 2; ILT-2; Monocyte/Macrophage Immunoglobulin-Like Receptor 7; MIR-7; CD85j; LILRB1; ILT2; LIR1; MIR7
分子量:74.1 kDa
組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.