背景：Leukocyte-Associated Immunoglobulin-Like Receptor 2 （LAIR2） is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily.
When compared to LAIR-1, its transmembrane counterpart, it shares 83％ amino acid identity across the signal sequence and extracellular domains; although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles.
This suggests that LAIR-2 may compete with LAIR-1 for ligand binding.
A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain.
The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.
仕様
サイズ：10ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞95 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：Q6ISS4
アミノ酸配列：Gln22-Pro152
遺伝子構造：Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gln22-Pro152 is expressed with a Fc tag at the C-terminus.
組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
