背景：Platelet Glycoprotein 4 （CD36） is an integral membrane glycoprotein that has multiple physiological functions.
It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia.
As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid （LCFA）, advanced glycation end products （AGE）, thrombospondin-1,oxidized lowdensity lipoproteins （oxLDLs）, high density lipoprotein （HDL）, phosphatidylserine, apoptotic cells, β amyloid fibrils （fAβ）, collagens I and IV, and Plasmodium falciparuminfected erythrocytes.
CD36 is required for the antiangiogenic effects of thrombospondin-1 in the corneal neovascularization assay.
It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues.
仕様
サイズ：10ug
種由来：Human
発現宿主：HEK293 Cells
純度：＞90 ％ as determined by reducing SDS-PAGE.
エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.：P16671
アミノ酸配列：Gly30-Asn439
遺伝子構造：Recombinant Human platelet membrane glycoprotein IV is produced by our Mammalian expression system and the target gene encoding Gly30-Asn439 is expressed with a Fc tag at the C-terminus.
組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
