特徴
- 背景:Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without asignal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens.
- The expression of MIF at sites ofinflammation suggests a role as mediator in regulating the function of acrophages in host defense.Counteracts the anti-inflammatory activity of glucocorticoids.
- Has phenylpyruvate tautomerase anddopachrome tautomerase activity (in vitro), but the physiological substrate is not known.
- It is not clearwhether the tautomerase activity has any physiological relevance, and whether it is important for cytokineactivity.
仕様
- サイズ:100ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:>95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:P14174
- アミノ酸配列:Met 1-Ala115
- 遺伝子構造:Recombinant Human Macrophage migration inhibitory factor is produced by our E.coli expression system and the target gene encoding Met1-Ala115 is expressed.
- 別名(遺伝子名):Macrophage migration inhibitory factor; MIF; MMIF; Glycosylation-inhibiting factor; GLIF; L-dopachrome tautomerase; Phenylpyruvate tautomerase
- 分子量:12.5 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,20% Glycerol,pH7.4.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9365-74
Recombinant Human MIF Protein 20ug
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84-9365-75
Recombinant Human MIF Protein 100ug
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