背景:IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes.
It is structurally different from type I interferon and its major activity is immunoregulation.
It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them; leading to autoimmune disease.
Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens; mitogens; or alloantigens.
It is produced by lymphocytes expressing the surface antigens CD4 and CD8.
IFNγ synthesis is induced by IL-2; FGF-basic; and EGF.
仕様
サイズ:100ug
種由来:Human
発現宿主:E.coli
純度:>95 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.:P01579
アミノ酸配列:Gln24-Gln166
遺伝子構造:Recombinant Human Interferon gamma is produced by our E.coli expression system and the target gene encoding Gln24-Gln166 is expressed.
組成:Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.0.
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.