特徴
- 背景：Glial Cell Line-Derived Neurotrophic Factor （GDNF） is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily.
- It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development.
- Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein.
- Mature human GDNF was predicted to contain two 134 amino acid residue subunits.
- Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells.
- Mutations in this gene may be associated with Hirschsprung disease.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：＞95 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：P39905
- アミノ酸配列：Ser78-Ile211
- 遺伝子構造：Recombinant Human Glial Cell Line-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ser78-Ile211 is expressed.
- 別名（遺伝子名）：Glial Cell Line-Derived Neurotrophic Factor; hGDNF; Astrocyte-Derived Trophic Factor; ATF; GDNF
- 分子量：15.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.25.
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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- アズワン株式会社 試薬・プロセス材料グループ
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- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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84-9365-43
Recombinant Human GDNF Protein （Active） 100ug
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84-9365-42
Recombinant Human GDNF Protein （Active） 20ug
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