背景:The leukocyte immunoglobulin-like receptor (LILR) B4 belongs to a family of cell surface receptors that possesses cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1.
LILRB4 is associated with the pathological processes of various inflammatory diseases.The LILRB4 is a central inhibitory receptor in uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface.
仕様
サイズ:1mg
種由来:Human
発現宿主:HEK293 Cells
純度:>95 % as determined by reducing SDS-PAGE.
エンドトキシン濃度:<1.0 EU per μg of the protein as determined by the LAL method.
アクセッションNo.:NP_001265356.2
アミノ酸配列:Met 1-His257
遺伝子構造:A DNA sequence encoding the human LILRB4 (NP_001265356.2) (Met1-His257) was expressed with the Fc region of human IgG1 at the C-terminus.
別名(遺伝子名):CD85K;ILT-3;ILT3;LIR-5;LIR5
分子量:52.8 kDa
組成:Lyophilized from sterile PBS, pH 7.4
保存条件:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.