84-9364-76 Recombinant Human Carbonic Anhydrase 9/CA9 Protein （Fc Tag）（Active） 1mg PKSH031872
[Elabscience]
特徴
- 背景：Carbonic anhydrases IX （CA IX）, also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase （CA） family and may be involved in cell proliferation and cellular transformation.
- CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide （H2O + CO2 = H+ + HCO3＆ndash;） and thus participate in a variety of biological and physical processes.
- CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions.
- It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control.
- CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.
仕様
- サイズ：1mg
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：＞90 ％ as determined by reducing SDS-PAGE.
- エンドトキシン濃度：＜1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.：NP_001207.2
- アミノ酸配列：Met 1-Asp 414
- 遺伝子構造：A DNA sequence encoding the human carbonic anhydrase IX （CA9） precursor （NP_001207.2） （Met 1-Asp 414） was fused with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：CAIX;Carbonic Anhydrase IX;MN
- 分子量：67.7 kDa
- 組成：Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5
- 保存条件：Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months.
- メーカーマニュアルリンク：メーカーマニュアルはこちら
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
84-9364-75
Recombinant Human Carbonic Anhydrase 9/CA9 Protein （Fc Tag）（Active） 50ug
|
|
|
84-9364-76
Recombinant Human Carbonic Anhydrase 9/CA9 Protein （Fc Tag）（Active） 1mg
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|